Protagonist Therapeutics, Inc
PTGXNasdaqCIK 1377121Healthcare / Drug Manufacturersfiscal year ends December47 quarters since 2015
Latest quarter Q3 FY2026, filed November 6, 2026. Trailing figures sum the latest four quarters. Market values at the latest close, from a market data vendor.
Share price
Daily candlesticks from November 11, 2024 to November 6, 2026, with each earnings release marked; a release after the close marks the day it came out, so its reaction is the next candle. See this earnings season for every company’s reaction.
The last 16 quarters
Q4 FY2022 to Q3 FY2026, through the filing of November 6, 2026.
Net income losses drawn in red.
Operating cash flow less capital expenditures; negative quarters in red.
Positions at each quarter end, as filed; short-term investments are not included.
Income statement
Last eight quarters, newest first, through Q3 FY2026 filed November 6, 2026.
| Millions of dollars | Q3 FY2026ended Sep 30, 2026filed Nov 6, 2026 | Q2 FY2026ended Jun 30, 2026filed Aug 5, 2026 | Q1 FY2026ended Mar 31, 2026filed May 5, 2026 | Q4 FY2025ended Dec 31, 2025filed Feb 25, 2026 | Q3 FY2025ended Sep 30, 2025filed Nov 6, 2025 | Q2 FY2025ended Jun 30, 2025filed Aug 6, 2025 | Q1 FY2025ended Mar 31, 2025filed May 6, 2025 | Q4 FY2024ended Dec 31, 2024filed Feb 21, 2025 | YoYQ3 FY2026vs Q3 FY2025 |
|---|---|---|---|---|---|---|---|---|---|
| Revenue | 274 | 213 | 56 | 7 | 5 | 6 | 28 | 171 | +5723.6% |
| Cost of revenue | 1 | — | — | — | — | — | — | — | — |
| Gross profit | — | — | — | — | — | — | — | — | — |
| Research and development | 41 | 42 | 47 | 46 | 40 | 37 | 36 | 35 | +3.2% |
| Selling, general and administrative | 14 | 13 | 13 | 11 | 11 | 11 | 12 | 9 | +23.1% |
| Operating income | 218 | 159 | (4) | (50) | (46) | (42) | (19) | 127 | +570.3% |
| Other income (expense) | 0 | 0 | 0 | 0 | 0 | — | — | 0 | −142.4% |
| Pretax income | 227 | 165 | 2 | (44) | (39) | (35) | (12) | 134 | +675.9% |
| Income tax | 7 | 2 | (2) | 1 | 0 | 0 | 0 | 2 | — |
| Net income | 220 | 163 | 4 | (44) | (39) | (35) | (12) | 132 | +659.3% |
| Diluted EPS ($) | 3.07 | 2.29 | 0.05 | — | (0.62) | (0.55) | (0.19) | — | +595.2% |
| Diluted shares (millions) | 72 | 71 | 70 | — | 64 | 64 | 63 | — | — |
Fourth quarters are the fiscal year less the first nine months when the filer reports no discrete fourth quarter, and are marked. Diluted EPS is never derived, so a derived quarter shows none. Italic figures are derived.
Balance sheet
Last eight quarters, newest first, through Q3 FY2026 filed November 6, 2026.
| Millions of dollars | Q3 FY2026ended Sep 30, 2026filed Nov 6, 2026 | Q2 FY2026ended Jun 30, 2026filed Aug 5, 2026 | Q1 FY2026ended Mar 31, 2026filed May 5, 2026 | Q4 FY2025ended Dec 31, 2025filed Feb 25, 2026 | Q3 FY2025ended Sep 30, 2025filed Nov 6, 2025 | Q2 FY2025ended Jun 30, 2025filed Aug 6, 2025 | Q1 FY2025ended Mar 31, 2025filed May 6, 2025 | Q4 FY2024ended Dec 31, 2024filed Feb 21, 2025 | YoYQ3 FY2026vs Q3 FY2025 |
|---|---|---|---|---|---|---|---|---|---|
| Cash and equivalents | 498 | 420 | 194 | 128 | 114 | 169 | 140 | 97 | +338.2% |
| Short-term investments | 302 | 362 | 354 | 439 | 462 | 402 | 435 | 322 | −34.7% |
| Total current assets | 1,101 | 807 | 613 | 578 | 586 | 603 | 606 | 592 | +87.8% |
| Total assets | 1,147 | 886 | 697 | 668 | 702 | 718 | 742 | 745 | +63.4% |
| Total current liabilities | 55 | 37 | 35 | 45 | 45 | 36 | 35 | 47 | +23.4% |
| Long-term debt | — | — | — | — | — | — | — | — | — |
| Total liabilities | 62 | 44 | 42 | 53 | 56 | 50 | 53 | 69 | +9.6% |
| Stockholders’ equity | 1,085 | 842 | 655 | 615 | 645 | 668 | 689 | 675 | +68.1% |
| Shares outstanding (millions) | 65 | 65 | 64 | 64 | 63 | 62 | 62 | 61 | — |
Positions at each period end. Nothing on this statement is derived. Long-term debt is the filed noncurrent line only; no total-debt composite is constructed across filers. Italic figures are derived.
Cash flow statement
Last eight quarters, newest first, through Q3 FY2026 filed November 6, 2026.
| Millions of dollars | Q3 FY2026ended Sep 30, 2026filed Nov 6, 2026 | Q2 FY2026ended Jun 30, 2026filed Aug 5, 2026 | Q1 FY2026ended Mar 31, 2026filed May 5, 2026 | Q4 FY2025ended Dec 31, 2025filed Feb 25, 2026 | Q3 FY2025ended Sep 30, 2025filed Nov 6, 2025 | Q2 FY2025ended Jun 30, 2025filed Aug 6, 2025 | Q1 FY2025ended Mar 31, 2025filed May 6, 2025 | Q4 FY2024ended Dec 31, 2024filed Feb 21, 2025 | YoYQ3 FY2026vs Q3 FY2025 |
|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | (23) | 219 | (49) | (37) | (2) | (29) | 125 | (29) | −1098.8% |
| Capital expenditures | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | +169.3% |
| Free cash flow (CFO − capex) | (23) | 219 | (49) | (37) | (2) | (30) | 125 | (29) | −1058.4% |
| Depreciation and amortization | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | +13.3% |
| Share repurchases | — | — | — | — | — | — | — | — | — |
| Dividends paid | — | — | — | — | — | — | — | — | — |
10-Qs file cash flows as year-to-date totals, so quarterly figures are differenced from consecutive filings and marked. Free cash flow is operating cash flow less capital expenditures, computed from the two filed lines. Italic figures are derived.
Annual statements
Every fiscal year filed, newest first, through FY2025 filed February 25, 2026.
Income statement
| Millions of dollars | FY2025ended Dec 31, 2025filed Feb 25, 2026 | FY2024ended Dec 31, 2024filed Feb 21, 2025 | FY2023ended Dec 31, 2023filed Feb 27, 2024 | FY2022ended Dec 31, 2022filed Mar 15, 2023 | FY2021ended Dec 31, 2021filed Feb 28, 2022 | FY2020ended Dec 31, 2020filed Mar 10, 2021 | FY2019ended Dec 31, 2019filed Mar 10, 2020 | FY2018ended Dec 31, 2018filed Mar 12, 2019 | FY2017ended Dec 31, 2017filed Mar 7, 2018 | FY2016ended Dec 31, 2016filed Mar 7, 2017 | FY2015ended Dec 31, 2015filed Sep 15, 2016 | FY2014ended Dec 31, 2014filed Sep 15, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue | 46 | 434 | 60 | 27 | 27 | 29 | 0 | 31 | 20 | — | — | — |
| Cost of revenue | — | — | — | — | — | — | — | — | — | — | — | — |
| Gross profit | — | — | — | — | — | — | — | — | — | — | — | — |
| Research and development | 159 | 138 | 120 | 126 | 126 | 75 | 65 | 59 | 46 | 26 | 12 | 7 |
| Selling, general and administrative | 45 | 43 | 33 | 32 | 27 | 19 | 16 | 14 | 12 | 7 | 3 | 2 |
| Operating income | (158) | 253 | (94) | (131) | (126) | (65) | (81) | (42) | (38) | (33) | (15) | (9) |
| Other income (expense) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | — | — |
| Pretax income | (129) | 279 | (79) | (127) | (126) | (65) | (78) | (40) | (37) | (37) | (15) | — |
| Income tax | 1 | 4 | 0 | 0 | 0 | 1 | (1) | (1) | 0 | 0 | 0 | 0 |
| Net income | (130) | 275 | (79) | (127) | (126) | (66) | (77) | (39) | (37) | (37) | (15) | (11) |
| Diluted EPS ($) | (2.05) | 4.23 | (1.39) | (2.60) | (2.71) | (1.92) | — | — | — | — | — | — |
| Diluted shares (millions) | 64 | 65 | 57 | 49 | 46 | 34 | — | — | — | — | — | — |
Balance sheet
| Millions of dollars | FY2025ended Dec 31, 2025filed Feb 25, 2026 | FY2024ended Dec 31, 2024filed Feb 21, 2025 | FY2023ended Dec 31, 2023filed Feb 27, 2024 | FY2022ended Dec 31, 2022filed Mar 15, 2023 | FY2021ended Dec 31, 2021filed Feb 28, 2022 | FY2020ended Dec 31, 2020filed Mar 10, 2021 | FY2019ended Dec 31, 2019filed Mar 10, 2020 | FY2018ended Dec 31, 2018filed Mar 12, 2019 | FY2017ended Dec 31, 2017filed Mar 7, 2018 | FY2016ended Dec 31, 2016filed Mar 7, 2017 | FY2015ended Dec 31, 2015filed Sep 15, 2016 | FY2014ended Dec 31, 2014filed Sep 15, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cash and equivalents | 128 | 97 | 187 | 126 | 124 | 117 | 33 | 82 | 106 | 21 | 4 | 9 |
| Short-term investments | 439 | 322 | 155 | 112 | 203 | 188 | 100 | 47 | — | — | — | — |
| Total current assets | 578 | 592 | 356 | 243 | 341 | 316 | 145 | 138 | 151 | 83 | 14 | — |
| Total assets | 668 | 745 | 358 | 248 | 348 | 324 | 155 | 139 | 164 | 94 | 15 | — |
| Total current liabilities | 45 | 47 | 21 | 31 | 44 | 40 | 35 | 26 | 43 | 6 | 3 | — |
| Long-term debt | — | — | — | — | — | — | 10 | — | — | — | — | — |
| Total liabilities | 53 | 69 | 21 | 32 | 48 | 45 | 75 | 27 | 43 | 6 | 5 | — |
| Stockholders’ equity | 615 | 675 | 337 | 216 | 300 | 280 | 80 | 113 | 121 | 88 | (27) | (13) |
| Shares outstanding (millions) | 64 | 61 | 58 | 51 | 48 | 44 | 27 | 23 | 21 | 17 | — | — |
Cash flow statement
| Millions of dollars | FY2025ended Dec 31, 2025filed Feb 25, 2026 | FY2024ended Dec 31, 2024filed Feb 21, 2025 | FY2023ended Dec 31, 2023filed Feb 27, 2024 | FY2022ended Dec 31, 2022filed Mar 15, 2023 | FY2021ended Dec 31, 2021filed Feb 28, 2022 | FY2020ended Dec 31, 2020filed Mar 10, 2021 | FY2019ended Dec 31, 2019filed Mar 10, 2020 | FY2018ended Dec 31, 2018filed Mar 12, 2019 | FY2017ended Dec 31, 2017filed Mar 7, 2018 | FY2016ended Dec 31, 2016filed Mar 7, 2017 | FY2015ended Dec 31, 2015filed Sep 15, 2016 | FY2014ended Dec 31, 2014filed Sep 15, 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Operating cash flow | 58 | 184 | (70) | (108) | (108) | (72) | (42) | (50) | 4 | (30) | (14) | — |
| Capital expenditures | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
| Free cash flow (CFO − capex) | 56 | 183 | (71) | (109) | (109) | (73) | (42) | (50) | 3 | (30) | (15) | — |
| Depreciation and amortization | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 |
| Share repurchases | — | — | — | — | — | — | — | — | — | — | — | — |
| Dividends paid | — | — | — | — | — | — | — | — | — | — | — | — |
Insider activity
Form 4 filings by officers, directors and 10% owners, November 9, 2024 to November 9, 2026. Only open-market purchases and sales count as buys and sells; awards, exercises, tax withholding and gifts are listed in grey and never counted.
The last 25 transactions
| Traded | Insider | Role | Transaction | Shares | Price | Value | Held after | Filed |
|---|---|---|---|---|---|---|---|---|
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | option exercise | 9,229 | $38.98 | $360K | 68,232 | Oct 2, 2026 |
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | option exercise | 28,438 | $23.42 | $666K | 96,670 | Oct 2, 2026 |
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | option exercise | 15,650 | $19.19 | $300K | 112,320 | Oct 2, 2026 |
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | option exercise | 5,312 | $12.17 | $65K | 117,632 | Oct 2, 2026 |
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | open-market sale10b5-1 | 12,595 | $141.77 | $2M | 105,037 | Oct 2, 2026 |
| Sep 30, 2026 | Ali Asif | Chief Financial Officer | open-market sale10b5-1 | 46,034 | $141.78 | $7M | 59,003 | Oct 2, 2026 |
| Sep 10, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 7,278 | $21.58 | $157K | 530,246 | Sep 10, 2026 |
| Sep 10, 2026 | Patel Dinesh V PH D | President and CEO, Director | open-market sale10b5-1 | 7,278 | $144.10 | $1M | 522,968 | Sep 10, 2026 |
| Sep 9, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 63,548 | $21.58 | $1M | 586,516 | Sep 10, 2026 |
| Sep 9, 2026 | Patel Dinesh V PH D | President and CEO, Director | open-market sale10b5-1 | 63,548 | $146.18 | $9M | 522,968 | Sep 10, 2026 |
| Sep 8, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 54,174 | $21.58 | $1M | 577,142 | Sep 10, 2026 |
| Sep 8, 2026 | Patel Dinesh V PH D | President and CEO, Director | open-market sale10b5-1 | 54,174 | $145.87 | $8M | 522,968 | Sep 10, 2026 |
| Sep 3, 2026 | Patel Dinesh V PH D | President and CEO, Director | gift | 510 | $0.00 | — | 522,968 | Sep 8, 2026 |
| Aug 11, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 34,239 | $21.58 | $739K | 557,717 | Aug 12, 2026 |
| Aug 11, 2026 | Patel Dinesh V PH D | President and CEO, Director | open-market sale10b5-1 | 34,239 | $148.52 | $5M | 523,478 | Aug 12, 2026 |
| Aug 10, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 65,761 | $21.58 | $1M | 589,239 | Aug 12, 2026 |
| Aug 10, 2026 | Patel Dinesh V PH D | President and CEO, Director | open-market sale10b5-1 | 65,761 | $149.11 | $10M | 523,478 | Aug 12, 2026 |
| Jun 23, 2026 | Waddill William D. | Director | option exercise | 9,000 | $16.54 | $149K | 16,825 | Jun 25, 2026 |
| Jun 23, 2026 | Waddill William D. | Director | open-market sale10b5-1 | 9,000 | $117.94 | $1M | 7,825 | Jun 25, 2026 |
| Jun 10, 2026 | Waddill William D. | Director | option exercise | 3,000 | $11.80 | $35K | 10,825 | Jun 11, 2026 |
| Jun 10, 2026 | Waddill William D. | Director | option exercise | 6,000 | $16.54 | $99K | 16,825 | Jun 11, 2026 |
| Jun 10, 2026 | Waddill William D. | Director | open-market sale10b5-1 | 9,000 | $107.68 | $969K | 7,825 | Jun 11, 2026 |
| May 29, 2026 | Waddill William D. | Director | option exercise | 9,000 | $11.80 | $106K | 16,825 | Jun 1, 2026 |
| May 29, 2026 | Waddill William D. | Director | open-market sale10b5-1 | 9,000 | $99.64 | $897K | 7,825 | Jun 1, 2026 |
| May 12, 2026 | Patel Dinesh V PH D | President and CEO, Director | option exercise | 75,000 | $21.58 | $2M | 598,478 | May 14, 2026 |
Full insider history for Protagonist Therapeutics, Inc, or insider activity across all companies. A record of filings, not a recommendation.
Tracked funds holding it
2 of the tracked managers held PTGX in their latest 13F filing, through August 14, 2026. Weight is the share of the fund’s reported portfolio. How the funds have traded PTGX by quarter.
| Fund | Manager | Quarter | Value | Shares | Weight | Move |
|---|---|---|---|---|---|---|
| Duquesne Family Office | Stanley Druckenmiller | Q2 2026 | $26M | 208,900 | 0.49% | added +30.8% |
| Baron Capital Group | Ron Baron | Q2 2026 | $2M | 16,000 | 0.00% | added +6.7% |
Sources
Fiscal year ends in month 12; periods are labeled with the issuer's own fiscal calendar. Values are as most recently filed (restatements apply; per-share values are on current split basis per the connector's split table, flagged in adjusted). Flow items flagged in `derived` were computed (Q4 = FY − nine months; quarterly cash flow differenced from year-to-date filings) rather than read from a filing. `reconciliation.repaired` lists periods where a full-year figure was filed in a quarter slot: that row was dropped and the quarter rebuilt from the annual figure. `reconciliation.quarantined` lists periods where four filed quarters do not sum to the filed year — those quarterly values are withheld, so a blank there is a withholding rather than an absence of reporting.
- Filer
- PROTAGONIST THERAPEUTICS, INC., CIK 1377121 on EDGAR
- Extract generated
- November 8, 2026
- Withheld
- none
- Repaired
- 4 quarters where a full-year figure was filed in a quarter slot and the quarter was rebuilt: other income FY2019, revenue FY2019, other income FY2023, other income FY2025
XBRL concepts behind each line
Income statement
RevenueFromContractWithCustomerExcludingAssessedTax, RevenueFromContractWithCustomerIncludingAssessedTax, RevenuesCostOfRevenueResearchAndDevelopmentExpenseGeneralAndAdministrativeExpenseOperatingIncomeLossOtherNonoperatingIncomeExpenseIncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterestIncomeTaxExpenseBenefitNetIncomeLossEarningsPerShareDilutedWeightedAverageNumberOfDilutedSharesOutstandingBalance sheet
CashAndCashEquivalentsAtCarryingValueMarketableSecuritiesCurrentAssetsCurrentAssetsLiabilitiesCurrentLongTermDebtLiabilitiesStockholdersEquitydei:EntityCommonStockSharesOutstandingCash flow statement
NetCashProvidedByUsedInOperatingActivitiesPaymentsToAcquirePropertyPlantAndEquipmentDepreciationDepletionAndAmortizationPaymentsForRepurchaseOfCommonStockThe data
The statements on this page as files, generated November 8, 2026.
- JSON file
/data/financials/PTGX.json