The Filings Report

Protagonist Therapeutics, Inc insider trading

PTGXfinancial statementsForm 4 filings on EDGAR145 transactions since Nov 9, 2024

From August 12, 2026 to November 9, 2026, 0 insiders at Protagonist Therapeutics, Inc bought $0 of stock in the open market, and 2 sold $27M. Officers and directors accounted for $0 of purchases and $27M of sales. The last reported transaction was an option exercise by Ali Asif on September 30, 2026.

The answer card and chart use the same period. Change the range above the chart to update both. Form 4 filings through October 2, 2026; awards, option exercises, tax withholding and gifts are excluded from these totals.

Stock price and insider activity

Daily price candles with insider purchases and sales directly beneath them on the same timeline. Bars show individual days; totals sum all days in the selected period.

PTGX daily priceSplit-adjusted prices in US dollars

Bought $0Sold $27MAug 12, 2026 – Nov 9, 2026

Nov 6, 2026O $135.26 · H $138.40 · L $128.00 · C $132.04Bought $0 (0)Sold $0 (0)
$124$134$144$153$1632026-08-12: open $148.21, high $152.70, low $147.33, close $152.012026-08-13: open $153.15, high $154.99, low $150.92, close $151.422026-08-14: open $150.23, high $155.53, low $149.17, close $155.102026-08-17: open $155.11, high $158.95, low $153.60, close $158.622026-08-18: open $157.96, high $160.00, low $156.81, close $157.342026-08-19: open $160.81, high $160.81, low $154.22, close $154.942026-08-20: open $152.45, high $155.25, low $148.28, close $150.692026-08-21: open $152.10, high $154.95, low $150.82, close $154.322026-08-24: open $154.32, high $158.08, low $149.94, close $154.722026-08-25: open $155.84, high $157.98, low $150.09, close $150.592026-08-26: open $150.36, high $152.07, low $147.69, close $151.502026-08-27: open $150.35, high $151.68, low $147.11, close $149.502026-08-28: open $147.73, high $147.95, low $142.43, close $144.332026-08-31: open $143.26, high $149.30, low $141.95, close $147.752026-09-01: open $147.75, high $150.34, low $144.73, close $146.492026-09-02: open $148.00, high $149.42, low $144.61, close $146.082026-09-03: open $146.68, high $149.49, low $144.00, close $148.802026-09-04: open $146.47, high $147.99, low $144.01, close $145.722026-09-08: open $143.61, high $147.29, low $142.00, close $145.942026-09-09: open $146.05, high $151.19, low $144.46, close $145.092026-09-10: open $143.29, high $146.51, low $142.00, close $145.162026-09-11: open $147.18, high $150.48, low $145.82, close $148.182026-09-14: open $150.23, high $151.24, low $146.83, close $147.782026-09-15: open $147.48, high $147.99, low $142.00, close $143.402026-09-16: open $144.19, high $146.19, low $140.88, close $142.842026-09-17: open $144.39, high $146.50, low $142.31, close $143.702026-09-18: open $143.09, high $144.58, low $140.44, close $143.002026-09-21: open $143.22, high $145.37, low $141.09, close $144.982026-09-22: open $144.64, high $147.71, low $144.50, close $145.072026-09-23: open $144.27, high $145.28, low $137.88, close $138.702026-09-24: open $138.76, high $140.80, low $134.10, close $137.342026-09-25: open $141.81, high $143.45, low $138.23, close $141.862026-09-28: open $142.21, high $143.69, low $140.24, close $142.442026-09-29: open $143.45, high $144.09, low $138.88, close $140.972026-09-30: open $141.60, high $143.74, low $140.44, close $140.892026-10-01: open $139.23, high $143.68, low $138.37, close $139.192026-10-02: open $140.99, high $141.71, low $138.37, close $140.062026-10-05: open $139.96, high $142.51, low $138.08, close $140.632026-10-06: open $140.34, high $141.00, low $136.09, close $138.692026-10-07: open $137.34, high $144.10, low $137.25, close $140.922026-10-08: open $139.57, high $142.18, low $137.99, close $139.912026-10-09: open $139.91, high $146.30, low $138.95, close $143.732026-10-12: open $145.83, high $152.19, low $143.69, close $144.882026-10-13: open $146.00, high $146.00, low $137.81, close $138.492026-10-14: open $138.06, high $141.13, low $135.62, close $136.282026-10-15: open $136.72, high $139.11, low $136.03, close $136.552026-10-16: open $136.16, high $136.56, low $126.39, close $128.752026-10-19: open $130.09, high $134.97, low $128.01, close $134.442026-10-20: open $135.87, high $140.82, low $134.33, close $137.992026-10-21: open $139.71, high $141.85, low $137.96, close $138.082026-10-22: open $137.49, high $141.38, low $136.07, close $139.532026-10-23: open $136.89, high $139.52, low $135.00, close $138.432026-10-26: open $139.24, high $142.00, low $137.30, close $140.322026-10-27: open $140.08, high $142.37, low $137.91, close $141.122026-10-28: open $139.35, high $143.26, low $138.29, close $142.142026-10-29: open $144.03, high $146.44, low $142.87, close $144.342026-10-30: open $144.34, high $146.00, low $142.54, close $144.852026-11-02: open $145.74, high $146.01, low $139.35, close $139.372026-11-03: open $140.73, high $144.27, low $139.91, close $140.242026-11-04: open $145.61, high $145.61, low $138.39, close $143.372026-11-05: open $142.56, high $143.30, low $134.39, close $135.262026-11-06: open $135.26, high $138.40, low $128.00, close $132.04Insider purchases / sales · USD$10M$0−$10M2026-09-08: 0 purchases ($0), 1 sales ($8M)2026-09-09: 0 purchases ($0), 1 sales ($9M)2026-09-10: 0 purchases ($0), 1 sales ($1M)2026-09-30: 0 purchases ($0), 2 sales ($8M)Aug 12Sep 2Sep 25Oct 16Nov 6

purchases above zero; sales below. Both use the transaction date and the same dollar scale. Hover, tap, or use arrow keys to inspect a date. Awards, exercises, tax withholding and gifts are excluded.

Dates with prices or insider activity are spaced evenly; empty weekends and holidays are omitted. Prices through Nov 6, 2026. Insider data through Nov 9, 2026. Prices are adjusted for splits; transaction values are reported dollars.

Every transaction

145 transactions from November 9, 2024 to November 9, 2026, newest first. Open-market purchases and sales are coloured; awards, exercises, tax withholding and gifts are grey and not counted.

TradedInsiderRoleTransactionSharesPriceValueHeld afterFiled
Sep 30, 2026Ali AsifChief Financial Officeroption exercise9,229$38.98$360K68,232Oct 2, 2026
Sep 30, 2026Ali AsifChief Financial Officeroption exercise28,438$23.42$666K96,670Oct 2, 2026
Sep 30, 2026Ali AsifChief Financial Officeroption exercise15,650$19.19$300K112,320Oct 2, 2026
Sep 30, 2026Ali AsifChief Financial Officeroption exercise5,312$12.17$65K117,632Oct 2, 2026
Sep 30, 2026Ali AsifChief Financial Officeropen-market sale10b5-112,595$141.77$2M105,037Oct 2, 2026
Sep 30, 2026Ali AsifChief Financial Officeropen-market sale10b5-146,034$141.78$7M59,003Oct 2, 2026
Sep 10, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise7,278$21.58$157K530,246Sep 10, 2026
Sep 10, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-17,278$144.10$1M522,968Sep 10, 2026
Sep 9, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise63,548$21.58$1M586,516Sep 10, 2026
Sep 9, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-163,548$146.18$9M522,968Sep 10, 2026
Sep 8, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise54,174$21.58$1M577,142Sep 10, 2026
Sep 8, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-154,174$145.87$8M522,968Sep 10, 2026
Sep 3, 2026Patel Dinesh V PH DPresident and CEO, Directorgift510$0.00—522,968Sep 8, 2026
Aug 11, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise34,239$21.58$739K557,717Aug 12, 2026
Aug 11, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-134,239$148.52$5M523,478Aug 12, 2026
Aug 10, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise65,761$21.58$1M589,239Aug 12, 2026
Aug 10, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-165,761$149.11$10M523,478Aug 12, 2026
Jun 23, 2026Waddill William D.Directoroption exercise9,000$16.54$149K16,825Jun 25, 2026
Jun 23, 2026Waddill William D.Directoropen-market sale10b5-19,000$117.94$1M7,825Jun 25, 2026
Jun 10, 2026Waddill William D.Directoroption exercise3,000$11.80$35K10,825Jun 11, 2026
Jun 10, 2026Waddill William D.Directoroption exercise6,000$16.54$99K16,825Jun 11, 2026
Jun 10, 2026Waddill William D.Directoropen-market sale10b5-19,000$107.68$969K7,825Jun 11, 2026
May 29, 2026Waddill William D.Directoroption exercise9,000$11.80$106K16,825Jun 1, 2026
May 29, 2026Waddill William D.Directoropen-market sale10b5-19,000$99.64$897K7,825Jun 1, 2026
May 12, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise75,000$21.58$2M598,478May 14, 2026
May 12, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale10b5-175,000$100.12$8M523,478May 14, 2026
May 12, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise75,000$21.58$2M598,478May 12, 2026
May 12, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale75,000$100.12$8M523,478May 12, 2026
May 8, 2026Giraudo BryanDirectoropen-market saleindirect6,000$100.00$600K0May 11, 2026
May 8, 2026Giraudo BryanDirectoropen-market sale5,130$100.00$513K12,695May 11, 2026
May 7, 2026Giraudo BryanDirectoroption exercise24,000$6.45$155K31,825May 11, 2026
May 7, 2026Giraudo BryanDirectoroption exercise12,000$6.98$84K43,825May 11, 2026
May 7, 2026Giraudo BryanDirectoropen-market sale36,000$100.14$4M27,825May 11, 2026
May 7, 2026Giraudo BryanDirectoropen-market saleindirect12,000$100.07$1M6,000May 11, 2026
Apr 23, 2026Patel Dinesh V PH DPresident and CEO, Directorgift1,460$0.00—523,478Apr 24, 2026
Apr 20, 2026Ali AsifChief Financial Officeropen-market sale1,750$105.47$185K59,003Apr 21, 2026
Mar 26, 2026Molina Arturo MDChief Medical Officeropen-market sale15,000$104.79$2M84,115Mar 27, 2026
Mar 26, 2026Molina Arturo MDChief Medical Officeroption exercise15,000$8.04$121K99,115Mar 27, 2026
Mar 26, 2026Selick Harold EDirectoropen-market sale24,000$105.00$3M60,845Mar 27, 2026
Mar 26, 2026Selick Harold EDirectoroption exercise24,000$12.88$309K84,845Mar 27, 2026
Mar 26, 2026Ali AsifChief Financial Officeropen-market sale24,765$104.24$3M60,753Mar 27, 2026
Mar 26, 2026Ali AsifChief Financial Officeroption exercise5,265$12.17$64K85,518Mar 27, 2026
Mar 26, 2026Ali AsifChief Financial Officeroption exercise19,500$19.19$374K80,253Mar 27, 2026
Mar 25, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale54,641$101.00$6M524,938Mar 25, 2026
Mar 25, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise54,641$8.58$469K579,579Mar 25, 2026
Mar 24, 2026Patel Dinesh V PH DPresident and CEO, Directoroption exercise59$8.58$506524,997Mar 25, 2026
Mar 24, 2026Patel Dinesh V PH DPresident and CEO, Directoropen-market sale59$101.00$6K524,938Mar 25, 2026
Mar 23, 2026Patel Dinesh V PH DPresident and CEO, Directorgift50,000$0.00—524,938Mar 25, 2026
Feb 17, 2026Williams Lewis TDirectoroption exercise18,000$10.84$195K25,825Feb 18, 2026
Feb 17, 2026Williams Lewis TDirectoropen-market sale18,000$82.42$1M7,825Feb 18, 2026

Who the insiders are

Everyone who reported a transaction since November 9, 2024, by open-market value over twelve months. Shares held are after the insider’s latest directly held transaction.

InsiderRoleLast transactionKindShares heldBought, 12 monthsSold, 12 monthsSales under a plan
Patel Dinesh V PH DPresident and CEO, DirectorSep 10, 2026option exercise530,246—$61M (14)6 of 14
Ali AsifChief Financial OfficerSep 30, 2026option exercise68,232—$16M (7)2 of 7
Giraudo BryanDirectorMay 8, 2026open-market sale12,695—$6M (4)0 of 4
Waddill William D.DirectorJun 23, 2026option exercise16,825—$5M (4)3 of 4
Molina Arturo MDChief Medical OfficerMar 26, 2026open-market sale84,115—$4M (6)0 of 6
Selick Harold EDirectorMar 26, 2026open-market sale60,845—$3M (1)0 of 1
Williams Lewis TDirectorFeb 17, 2026option exercise25,825—$1M (1)0 of 1
Gupta SuneelChief Development OfficerNov 26, 2024open-market sale266,983———
O'Dowd Sarah ADirectorJan 2, 2026award7,825———

Questions

Are Protagonist Therapeutics, Inc insiders buying or selling?

Over the twelve months to November 9, 2026, 7 insiders at Protagonist Therapeutics, Inc sold $95M of stock in the open market, all by officers and directors, and no insider bought. Net, insiders sold $95M. Only open-market purchases and sales are counted.

Who sold the most Protagonist Therapeutics, Inc stock in the last year?

Patel Dinesh V PH D (President and CEO, Director) sold $61M in 14 open-market sales over the twelve months to November 9, 2026.

Do Protagonist Therapeutics, Inc executives sell under 10b5-1 plans?

11 of the 37 open-market sales in the last twelve months (30%) were reported as made under a Rule 10b5-1 trading plan, set up in advance. A sale under a plan is still counted as a sale.

What counts as insider buying here?

Only open-market purchases (Form 4 code P) and sales (code S) by officers, directors and 10% owners. Stock awards, option exercises, shares withheld for tax and gifts are listed in the table but never counted as buying or selling.

More on Protagonist Therapeutics, Inc

From Form 4, 4/A and 5 filings with the SEC. A record of insider transactions, not a recommendation.