The Filings Report

Alnylam Pharmaceuticals, Inc. insider trading

ALNYfinancial statementsForm 4 filings on EDGAR738 transactions since Nov 1, 2024

From August 4, 2026 to November 1, 2026, 0 insiders at Alnylam Pharmaceuticals, Inc. bought $0 of stock in the open market, and 1 sold $399K. Officers and directors accounted for $0 of purchases and $399K of sales. The last reported transaction was an open-market sale by Supran Bryan on October 2, 2026.

The answer card and chart use the same period. Change the range above the chart to update both. Form 4 filings through October 6, 2026; awards, option exercises, tax withholding and gifts are excluded from these totals.

Stock price and insider activity

Daily price candles with insider purchases and sales directly beneath them on the same timeline. Bars show individual days; totals sum all days in the selected period.

ALNY daily priceSplit-adjusted prices in US dollars

Bought $0Sold $399KAug 4, 2026 – Nov 1, 2026

Oct 30, 2026O $172.70 · H $180.61 · L $163.30 · C $165.00Bought $0 (0)Sold $0 (0)
$157$187$218$248$2792026-08-04: open $220.33, high $222.59, low $215.07, close $219.002026-08-05: open $221.74, high $229.65, low $221.50, close $228.722026-08-06: open $228.58, high $234.00, low $212.98, close $216.122026-08-07: open $217.31, high $219.64, low $210.49, close $219.202026-08-10: open $218.00, high $223.50, low $215.61, close $216.982026-08-11: open $217.41, high $223.44, low $216.50, close $221.202026-08-12: open $219.00, high $224.66, low $219.00, close $223.952026-08-13: open $225.95, high $227.54, low $222.70, close $227.122026-08-14: open $223.52, high $228.98, low $220.23, close $228.652026-08-17: open $225.76, high $227.99, low $222.12, close $224.602026-08-18: open $226.27, high $230.91, low $222.01, close $228.612026-08-19: open $234.36, high $244.03, low $233.40, close $242.612026-08-20: open $239.00, high $240.88, low $228.74, close $229.302026-08-21: open $228.88, high $238.97, low $228.34, close $236.222026-08-24: open $235.83, high $237.91, low $228.59, close $236.012026-08-25: open $236.56, high $240.67, low $235.41, close $240.082026-08-26: open $238.54, high $242.89, low $236.60, close $239.002026-08-27: open $236.56, high $238.00, low $230.46, close $236.562026-08-28: open $224.47, high $239.08, low $223.61, close $237.102026-08-31: open $235.94, high $243.02, low $233.33, close $240.692026-09-01: open $242.40, high $248.13, low $238.00, close $246.112026-09-02: open $246.48, high $269.94, low $246.48, close $267.402026-09-03: open $265.94, high $271.19, low $261.54, close $264.502026-09-04: open $258.58, high $266.85, low $258.02, close $266.112026-09-08: open $259.00, high $272.08, low $254.01, close $260.102026-09-09: open $257.07, high $261.98, low $253.28, close $258.002026-09-10: open $256.68, high $256.68, low $246.42, close $247.512026-09-11: open $248.05, high $254.08, low $246.01, close $248.672026-09-14: open $250.17, high $252.79, low $244.18, close $249.992026-09-15: open $246.99, high $247.43, low $237.44, close $238.272026-09-16: open $239.50, high $242.24, low $236.00, close $239.362026-09-17: open $242.60, high $245.63, low $239.50, close $245.512026-09-18: open $246.41, high $246.49, low $238.51, close $239.562026-09-21: open $240.37, high $247.10, low $237.97, close $244.322026-09-22: open $246.86, high $255.51, low $244.13, close $251.652026-09-23: open $249.99, high $253.81, low $245.34, close $246.512026-09-24: open $246.51, high $251.81, low $245.52, close $249.592026-09-25: open $248.39, high $256.52, low $247.51, close $255.962026-09-28: open $256.28, high $256.60, low $248.12, close $255.362026-09-29: open $254.86, high $257.27, low $251.02, close $254.072026-09-30: open $253.68, high $254.44, low $246.66, close $246.742026-10-01: open $248.21, high $251.71, low $230.06, close $231.042026-10-02: open $231.31, high $231.36, low $219.40, close $219.722026-10-05: open $218.36, high $222.08, low $215.46, close $219.892026-10-06: open $221.02, high $229.18, low $217.18, close $223.942026-10-07: open $224.39, high $230.42, low $222.46, close $224.412026-10-08: open $222.03, high $225.90, low $218.39, close $224.532026-10-09: open $224.74, high $232.94, low $222.71, close $232.682026-10-12: open $233.13, high $233.60, low $226.35, close $227.022026-10-13: open $228.93, high $229.53, low $221.56, close $223.822026-10-14: open $224.49, high $229.56, low $222.25, close $224.472026-10-15: open $230.00, high $234.30, low $228.12, close $234.032026-10-16: open $235.18, high $237.98, low $231.29, close $231.832026-10-19: open $232.65, high $236.54, low $231.26, close $233.292026-10-20: open $237.73, high $238.96, low $229.54, close $230.712026-10-21: open $227.86, high $230.84, low $224.88, close $225.102026-10-22: open $224.92, high $229.82, low $223.76, close $227.282026-10-23: open $227.28, high $229.39, low $222.00, close $224.032026-10-26: open $226.24, high $232.48, low $224.10, close $227.662026-10-27: open $225.00, high $228.49, low $222.82, close $226.792026-10-28: open $222.72, high $232.88, low $220.00, close $232.402026-10-29: open $185.59, high $202.37, low $172.31, close $174.002026-10-30: open $172.70, high $180.61, low $163.30, close $165.00Insider purchases / sales · USD$500K$0−$500K2026-10-02: 0 purchases ($0), 1 sales ($399K)Aug 4Aug 26Sep 17Oct 9Oct 30

purchases above zero; sales below. Both use the transaction date and the same dollar scale. Hover, tap, or use arrow keys to inspect a date. Awards, exercises, tax withholding and gifts are excluded.

Dates with prices or insider activity are spaced evenly; empty weekends and holidays are omitted. Prices through Oct 30, 2026. Insider data through Nov 1, 2026. Prices are adjusted for splits; transaction values are reported dollars.

Every transaction

738 transactions from November 1, 2024 to November 1, 2026, newest first. Open-market purchases and sales are coloured; awards, exercises, tax withholding and gifts are grey and not counted.

TradedInsiderRoleTransactionSharesPriceValueHeld afterFiled
Oct 2, 2026Supran BryanEVP, CLO and Secretaryopen-market sale1,758$226.88$399K12,807Oct 6, 2026
Sep 19, 2026Greenstreet YvonneChief Executive Officer, Directoraward107$0.00—95,802Sep 22, 2026
Jun 1, 2026Pyott David E IDirectoroption exercise3,830$0.00—5,412Jun 3, 2026
Jun 1, 2026Pyott David E IDirectoropen-market sale10b5-1921$297.71$274K4,491Jun 3, 2026
Jun 1, 2026Pyott David E IDirectoropen-market sale10b5-11,175$298.91$351K3,316Jun 3, 2026
Jun 1, 2026Pyott David E IDirectoropen-market sale10b5-11,222$299.87$366K2,094Jun 3, 2026
Jun 1, 2026Pyott David E IDirectoropen-market sale10b5-1495$300.72$149K1,599Jun 3, 2026
Jun 1, 2026Pyott David E IDirectoropen-market sale10b5-117$302.65$5K1,582Jun 3, 2026
May 20, 2026Sigal Charles ElliottDirectoraward671$0.00—1,446May 22, 2026
May 20, 2026Schulman Amy WDirectoraward838$0.00—24,049May 22, 2026
May 20, 2026Reitan Colleen FDirectoraward671$0.00—1,446May 22, 2026
May 20, 2026Pyott David E IDirectoraward671$0.00—1,582May 22, 2026
May 20, 2026Kellogg Peter NDirectoraward671$0.00—1,446May 22, 2026
May 20, 2026Hamburg Margaret ADirectoraward671$0.00—1,582May 22, 2026
May 20, 2026Brandicourt OlivierDirectoraward671$0.00—1,446May 22, 2026
May 20, 2026Ausiello Dennis ADirectoraward671$0.00—1,582May 22, 2026
May 20, 2026Arbuckle Stuart ADirectoraward671$0.00—671May 22, 2026
May 13, 2026Schulman Amy WDirectoroption exercise11,250$70.20$790K23,211May 14, 2026
Apr 6, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-156$320.14$18K11,673Apr 7, 2026
Apr 6, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1909$329.76$300K10,764Apr 7, 2026
Apr 6, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1829$330.46$274K9,935Apr 7, 2026
Apr 6, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1293$331.89$97K9,642Apr 7, 2026
Apr 6, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1199$333.94$66K9,443Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1265$316.61$84K13,088Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1359$317.44$114K12,729Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1209$318.47$67K12,520Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-186$319.69$27K12,434Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1147$320.62$47K12,287Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1224$321.64$72K12,063Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-1245$322.86$79K11,818Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-181$323.64$26K11,737Apr 7, 2026
Apr 2, 2026McLaughlin MelissaChief Human Resources Officeropen-market sale10b5-18$325.49$3K11,729Apr 7, 2026
Mar 5, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1500$326.08$163K18,693Mar 6, 2026
Mar 5, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1510$324.59$166K19,193Mar 6, 2026
Mar 5, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1740$323.55$239K19,703Mar 6, 2026
Mar 5, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1654$322.33$211K20,443Mar 6, 2026
Mar 5, 2026Fitzgerald Kevin JosephCSO & EVP, Head of Researchopen-market sale10b5-1124$321.81$40K21,103Mar 6, 2026
Mar 5, 2026Fitzgerald Kevin JosephCSO & EVP, Head of Researchopen-market sale10b5-1233$323.25$75K20,870Mar 6, 2026
Mar 5, 2026Fitzgerald Kevin JosephCSO & EVP, Head of Researchopen-market sale10b5-1148$324.60$48K20,722Mar 6, 2026
Mar 5, 2026Fitzgerald Kevin JosephCSO & EVP, Head of Researchopen-market sale10b5-1153$326.24$50K20,569Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1106$319.03$34K23,300Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1102$320.01$33K23,198Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1208$325.67$68K21,097Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1272$324.88$88K21,305Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1767$323.84$248K21,577Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1350$323.01$113K22,344Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1289$321.82$93K22,694Mar 6, 2026
Mar 4, 2026Garg PushkalEVP Chief R&Dopen-market sale10b5-1215$320.81$69K22,983Mar 6, 2026
Mar 4, 2026Greenstreet YvonneChief Executive Officer, Directoropen-market sale973$323.84$315K96,305Mar 6, 2026
Mar 4, 2026Greenstreet YvonneChief Executive Officer, Directoropen-market sale444$323.01$143K97,278Mar 6, 2026

Who the insiders are

Everyone who reported a transaction since November 1, 2024, by open-market value over twelve months. Shares held are after the insider’s latest directly held transaction.

InsiderRoleLast transactionKindShares heldBought, 12 monthsSold, 12 monthsSales under a plan
Greenstreet YvonneChief Executive Officer, DirectorSep 19, 2026award95,802—$20M (60)20 of 60
Fitzgerald Kevin JosephCSO & EVP, Head of ResearchMar 5, 2026open-market sale21,103—$10M (66)66 of 66
Garg PushkalEVP Chief R&DMar 5, 2026open-market sale18,693—$5M (53)31 of 53
Poulton Jeffrey V.EVP, Chief Financial OfficerMar 4, 2026open-market sale64,159—$3M (40)0 of 40
Tanguler TolgaEVP, Chief Commercial OfficerMar 4, 2026open-market sale35,894—$2M (40)0 of 40
McLaughlin MelissaChief Human Resources OfficerApr 6, 2026open-market sale11,673—$1M (14)14 of 14
Pyott David E IDirectorJun 1, 2026option exercise5,412—$1M (5)5 of 5
Supran BryanEVP, CLO and SecretaryOct 2, 2026open-market sale12,807—$399K (1)0 of 1
Reitan Colleen FDirectorMay 20, 2026award1,446———
Ausiello Dennis ADirectorMay 20, 2026award1,582———
Bonney Michael WDirectorAug 18, 2025open-market sale16,804———
Schulman Amy WDirectorMay 20, 2026award24,049———
Sigal Charles ElliottDirectorMay 20, 2026award1,446———
Kellogg Peter NDirectorMay 20, 2026award1,446———
Hamburg Margaret ADirectorMay 20, 2026award1,582———
Brandicourt OlivierDirectorMay 20, 2026award1,446———
Sharp Phillip ADirectorJan 23, 2025open-market sale0———
Arbuckle Stuart ADirectorMay 20, 2026award671———
Bertozzi Carolyn RDirectorMay 8, 2025award775———
Hesslein Robert W.EVP, CLO and SecretaryMar 3, 2025award8,002———

Questions

Are Alnylam Pharmaceuticals, Inc. insiders buying or selling?

Over the twelve months to November 1, 2026, 8 insiders at Alnylam Pharmaceuticals, Inc. sold $44M of stock in the open market, all by officers and directors, and no insider bought. Net, insiders sold $44M. Only open-market purchases and sales are counted.

Who sold the most Alnylam Pharmaceuticals, Inc. stock in the last year?

Greenstreet Yvonne (Chief Executive Officer, Director) sold $20M in 60 open-market sales over the twelve months to November 1, 2026.

Do Alnylam Pharmaceuticals, Inc. executives sell under 10b5-1 plans?

136 of the 279 open-market sales in the last twelve months (49%) were reported as made under a Rule 10b5-1 trading plan, set up in advance. A sale under a plan is still counted as a sale.

What counts as insider buying here?

Only open-market purchases (Form 4 code P) and sales (code S) by officers, directors and 10% owners. Stock awards, option exercises, shares withheld for tax and gifts are listed in the table but never counted as buying or selling.

More on Alnylam Pharmaceuticals, Inc.

From Form 4, 4/A and 5 filings with the SEC. A record of insider transactions, not a recommendation.