{"symbol":"RVMD","slug":"rvmd","name":"Revolution Medicines, Inc. Common Stock","cik":1628171,"as_of":"2026-11-01","history_from":"2024-11-01","transactions":294,"summary":{"3m":{"buys":0,"sells":80,"buyers":0,"sellers":9,"buy_value":0,"sell_value":78441238,"buy_shares":0,"sell_shares":383020,"buy_value_officers_directors":0,"sell_value_officers_directors":78441238,"net_value":-78441238},"12m":{"buys":0,"sells":158,"buyers":0,"sellers":12,"buy_value":0,"sell_value":153987200,"buy_shares":0,"sell_shares":1042724,"buy_value_officers_directors":0,"sell_value_officers_directors":153987200,"net_value":-153987200},"plan_sales_12m":157,"plan_share_of_sales_12m":99.4},"by_quarter":[{"period":"2025Q1","label":"Q1 2025","buys":0,"sells":7,"buy_value":0,"sell_value":1012375,"buyers":0,"sellers":5,"other":8,"partial":false},{"period":"2025Q2","label":"Q2 2025","buys":0,"sells":8,"buy_value":0,"sell_value":1729823,"buyers":0,"sellers":6,"other":8,"partial":false},{"period":"2025Q3","label":"Q3 2025","buys":0,"sells":13,"buy_value":0,"sell_value":7408396,"buyers":0,"sellers":6,"other":6,"partial":false},{"period":"2025Q4","label":"Q4 2025","buys":0,"sells":17,"buy_value":0,"sell_value":16575398,"buyers":0,"sellers":5,"other":16,"partial":false},{"period":"2026Q1","label":"Q1 2026","buys":0,"sells":31,"buy_value":0,"sell_value":18986539,"buyers":0,"sellers":8,"other":15,"partial":false},{"period":"2026Q2","label":"Q2 2026","buys":0,"sells":34,"buy_value":0,"sell_value":42912225,"buyers":0,"sellers":7,"other":20,"partial":false},{"period":"2026Q3","label":"Q3 2026","buys":0,"sells":79,"buy_value":0,"sell_value":78009291,"buyers":0,"sellers":9,"other":9,"partial":false},{"period":"2026Q4","label":"Q4 2026","buys":0,"sells":1,"buy_value":0,"sell_value":431947,"buyers":0,"sellers":1,"other":1,"partial":true}],"by_month":[{"period":"2024-12","label":"Dec 2024","buys":2,"sells":5,"buy_value":59999962,"sell_value":1132277,"buyers":1,"sellers":5,"other":1,"partial":false},{"period":"2025-01","label":"Jan 2025","buys":0,"sells":1,"buy_value":0,"sell_value":97443,"buyers":0,"sellers":1,"other":0,"partial":false},{"period":"2025-02","label":"Feb 2025","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2025-03","label":"Mar 2025","buys":0,"sells":6,"buy_value":0,"sell_value":914932,"buyers":0,"sellers":5,"other":8,"partial":false},{"period":"2025-04","label":"Apr 2025","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2025-05","label":"May 2025","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2025-06","label":"Jun 2025","buys":0,"sells":8,"buy_value":0,"sell_value":1729823,"buyers":0,"sellers":6,"other":8,"partial":false},{"period":"2025-07","label":"Jul 2025","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2025-08","label":"Aug 2025","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2025-09","label":"Sep 2025","buys":0,"sells":13,"buy_value":0,"sell_value":7408396,"buyers":0,"sellers":6,"other":6,"partial":false},{"period":"2025-10","label":"Oct 2025","buys":0,"sells":4,"buy_value":0,"sell_value":2928200,"buyers":0,"sellers":3,"other":4,"partial":false},{"period":"2025-11","label":"Nov 2025","buys":0,"sells":8,"buy_value":0,"sell_value":11228066,"buyers":0,"sellers":3,"other":12,"partial":false},{"period":"2025-12","label":"Dec 2025","buys":0,"sells":5,"buy_value":0,"sell_value":2419132,"buyers":0,"sellers":5,"other":0,"partial":false},{"period":"2026-01","label":"Jan 2026","buys":0,"sells":5,"buy_value":0,"sell_value":8627122,"buyers":0,"sellers":3,"other":3,"partial":false},{"period":"2026-02","label":"Feb 2026","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":1,"partial":false},{"period":"2026-03","label":"Mar 2026","buys":0,"sells":26,"buy_value":0,"sell_value":10359417,"buyers":0,"sellers":8,"other":11,"partial":false},{"period":"2026-04","label":"Apr 2026","buys":0,"sells":4,"buy_value":0,"sell_value":18423617,"buyers":0,"sellers":2,"other":3,"partial":false},{"period":"2026-05","label":"May 2026","buys":0,"sells":3,"buy_value":0,"sell_value":480611,"buyers":0,"sellers":1,"other":1,"partial":false},{"period":"2026-06","label":"Jun 2026","buys":0,"sells":27,"buy_value":0,"sell_value":24007997,"buyers":0,"sellers":7,"other":16,"partial":false},{"period":"2026-07","label":"Jul 2026","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":false},{"period":"2026-08","label":"Aug 2026","buys":0,"sells":31,"buy_value":0,"sell_value":41276644,"buyers":0,"sellers":3,"other":3,"partial":false},{"period":"2026-09","label":"Sep 2026","buys":0,"sells":48,"buy_value":0,"sell_value":36732647,"buyers":0,"sellers":9,"other":6,"partial":false},{"period":"2026-10","label":"Oct 2026","buys":0,"sells":1,"buy_value":0,"sell_value":431947,"buyers":0,"sellers":1,"other":1,"partial":false},{"period":"2026-11","label":"Nov 2026","buys":0,"sells":0,"buy_value":0,"sell_value":0,"buyers":0,"sellers":0,"other":0,"partial":true}],"owners":[{"name":"Goldsmith Mark A","cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"transactions":75,"last_date":"2026-09-16","last_kind":"open-market sale","last_form":"4","shares_after_last":267117.0,"bought_12m":0,"sold_12m":55708199,"buys_12m":0,"sells_12m":42,"plan_sales_12m":42},{"name":"Horn Margaret A","cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":32,"last_date":"2026-09-16","last_kind":"open-market sale","last_form":"4","shares_after_last":154571.0,"bought_12m":0,"sold_12m":25254156,"buys_12m":0,"sells_12m":16,"plan_sales_12m":16},{"name":"Kelsey Stephen Michael","cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":32,"last_date":"2026-09-16","last_kind":"open-market sale","last_form":"4","shares_after_last":291791.0,"bought_12m":0,"sold_12m":21332522,"buys_12m":0,"sells_12m":13,"plan_sales_12m":13},{"name":"Kim Lorence H.","cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":16,"last_date":"2026-09-08","last_kind":"open-market sale","last_form":"4","shares_after_last":74281.0,"bought_12m":0,"sold_12m":14967126,"buys_12m":0,"sells_12m":14,"plan_sales_12m":14},{"name":"Cislini Jeff","cik":"0001969082","title":"SVP & General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":33,"last_date":"2026-09-25","last_kind":"open-market sale","last_form":"4","shares_after_last":51776.0,"bought_12m":0,"sold_12m":14612608,"buys_12m":0,"sells_12m":15,"plan_sales_12m":15},{"name":"Mancini Anthony","cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":29,"last_date":"2026-10-26","last_kind":"option exercise","last_form":"4","shares_after_last":42075.0,"bought_12m":0,"sold_12m":10223034,"buys_12m":0,"sells_12m":23,"plan_sales_12m":22},{"name":"Anders Jack","cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":28,"last_date":"2026-09-16","last_kind":"open-market sale","last_form":"4","shares_after_last":123208.0,"bought_12m":0,"sold_12m":7133160,"buys_12m":0,"sells_12m":12,"plan_sales_12m":12},{"name":"Anderson Elizabeth M","cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":10,"last_date":"2026-09-22","last_kind":"option exercise","last_form":"4","shares_after_last":14476.0,"bought_12m":0,"sold_12m":1958015,"buys_12m":0,"sells_12m":5,"plan_sales_12m":5},{"name":"Sandler Alan B.","cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":8,"last_date":"2026-09-29","last_kind":"option exercise","last_form":"4","shares_after_last":58868.0,"bought_12m":0,"sold_12m":1343235,"buys_12m":0,"sells_12m":7,"plan_sales_12m":7},{"name":"Patel Sushil","cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":12,"last_date":"2026-06-29","last_kind":"option exercise","last_form":"4","shares_after_last":27236.0,"bought_12m":0,"sold_12m":1048968,"buys_12m":0,"sells_12m":9,"plan_sales_12m":9},{"name":"Wei Lin","cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":5,"last_date":"2026-03-17","last_kind":"open-market sale","last_form":"4","shares_after_last":101366.0,"bought_12m":0,"sold_12m":206222,"buys_12m":0,"sells_12m":1,"plan_sales_12m":1},{"name":"Wang Xiaolin","cik":"0001849181","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"transactions":4,"last_date":"2026-03-17","last_kind":"open-market sale","last_form":"4","shares_after_last":116063.0,"bought_12m":0,"sold_12m":199955,"buys_12m":0,"sells_12m":1,"plan_sales_12m":1},{"name":"Borisy Alexis","cik":"0001319446","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":2,"last_date":"2026-06-18","last_kind":"award","last_form":"4","shares_after_last":2340075.0,"bought_12m":0,"sold_12m":0,"buys_12m":0,"sells_12m":0,"plan_sales_12m":0},{"name":"Horning Sandra","cik":"0001638709","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":2,"last_date":"2026-06-18","last_kind":"award","last_form":"4","shares_after_last":97765.0,"bought_12m":0,"sold_12m":0,"buys_12m":0,"sells_12m":0,"plan_sales_12m":0},{"name":"Clyburn Frank","cik":"0001763963","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":2,"last_date":"2026-06-18","last_kind":"award","last_form":"4","shares_after_last":10929.0,"bought_12m":0,"sold_12m":0,"buys_12m":0,"sells_12m":0,"plan_sales_12m":0},{"name":"Borellini Flavia","cik":"0001867426","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":2,"last_date":"2026-06-18","last_kind":"award","last_form":"4","shares_after_last":26215.0,"bought_12m":0,"sold_12m":0,"buys_12m":0,"sells_12m":0,"plan_sales_12m":0},{"name":"Schroeder Thilo","cik":"0001776412","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"transactions":2,"last_date":"2024-12-05","last_kind":"open-market buy","last_form":"4","shares_after_last":null,"bought_12m":0,"sold_12m":0,"buys_12m":0,"sells_12m":0,"plan_sales_12m":0}],"rows":[{"accession":"0001193125-26-436459","form":"4","filed":"2026-10-28","date":"2026-10-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":2310.0,"price":33.62,"value":77662,"shares_after":42075.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526436459/"},{"accession":"0001193125-26-436459","form":"4","filed":"2026-10-28","date":"2026-10-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2310.0,"price":186.99,"value":431947,"shares_after":39765.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526436459/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":6000.0,"price":58.84,"value":353040,"shares_after":58868.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2200.0,"price":200.8188,"value":441801,"shares_after":56668.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1609.0,"price":201.7239,"value":324574,"shares_after":55059.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1000.0,"price":202.8127,"value":202813,"shares_after":54059.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1199.0,"price":203.9074,"value":244485,"shares_after":52860.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001835966-26-000008","form":"4","filed":"2026-10-01","date":"2026-09-29","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":301.0,"price":204.7224,"value":61621,"shares_after":52559.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000008/"},{"accession":"0001969082-26-000011","form":"4","filed":"2026-09-29","date":"2026-09-25","owner":"Cislini Jeff","owner_cik":"0001969082","title":"SVP & General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":765.0,"price":207.3201,"value":158600,"shares_after":51776.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000196908226000011/"},{"accession":"0002124509-26-000012","form":"4","filed":"2026-09-28","date":"2026-09-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3121.0,"price":33.62,"value":104928,"shares_after":42886.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000012/"},{"accession":"0002124509-26-000012","form":"4","filed":"2026-09-28","date":"2026-09-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3121.0,"price":200.54,"value":625885,"shares_after":39765.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000012/"},{"accession":"0002124509-26-000012","form":"4","filed":"2026-09-28","date":"2026-09-24","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":587.0,"price":200.0,"value":117400,"shares_after":39765.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000012/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":5070.0,"price":1.12,"value":5678,"shares_after":14476.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":910.0,"price":191.8521,"value":174585,"shares_after":13566.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4985.0,"price":192.5387,"value":959805,"shares_after":8581.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2648.0,"price":193.4392,"value":512227,"shares_after":5933.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1500.0,"price":194.5887,"value":291883,"shares_after":4433.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0001758247-26-000004","form":"4","filed":"2026-09-24","date":"2026-09-22","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":100.0,"price":195.15,"value":19515,"shares_after":4333.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000175824726000004/"},{"accession":"0002124509-26-000010","form":"4","filed":"2026-09-22","date":"2026-09-18","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1764.0,"price":196.94,"value":347402,"shares_after":40352.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000010/"},{"accession":"0001835966-26-000006","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5.0,"price":194.9589,"value":975,"shares_after":53204.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000006/"},{"accession":"0001835966-26-000006","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Sandler Alan B.","owner_cik":"0001835966","title":"Chief Development Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":336.0,"price":199.3032,"value":66966,"shares_after":52868.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000183596626000006/"},{"accession":"0002124509-26-000008","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":27.0,"price":195.0521,"value":5266,"shares_after":43863.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000008/"},{"accession":"0002124509-26-000008","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1747.0,"price":199.3032,"value":348183,"shares_after":42116.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000008/"},{"accession":"0001462808-26-000010","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":85.0,"price":195.0074,"value":16576,"shares_after":291791.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000010/"},{"accession":"0001462808-26-000010","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5484.0,"price":199.3032,"value":1092979,"shares_after":286307.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000010/"},{"accession":"0001294192-26-000007","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":76.0,"price":195.0083,"value":14821,"shares_after":154571.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000129419226000007/"},{"accession":"0001294192-26-000007","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4891.0,"price":199.3032,"value":974792,"shares_after":149680.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000129419226000007/"},{"accession":"0001246842-26-000008","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":213.0,"price":195.0085,"value":41537,"shares_after":267117.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000124684226000008/"},{"accession":"0001246842-26-000008","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13775.0,"price":199.3032,"value":2745402,"shares_after":253342.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000124684226000008/"},{"accession":"0001969082-26-000009","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"SVP & General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":52.0,"price":195.0087,"value":10140,"shares_after":55855.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000196908226000009/"},{"accession":"0001969082-26-000009","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"SVP & General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3314.0,"price":199.3032,"value":660491,"shares_after":52541.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000196908226000009/"},{"accession":"0001800668-26-000007","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":61.0,"price":195.0,"value":11895,"shares_after":123208.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000180066826000007/"},{"accession":"0001800668-26-000007","form":"4","filed":"2026-09-18","date":"2026-09-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3992.0,"price":199.3032,"value":795618,"shares_after":119216.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000180066826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":52500.0,"price":42.45,"value":2228625,"shares_after":344376.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":40031.0,"price":40.74,"value":1630863,"shares_after":384407.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":800.0,"price":198.5502,"value":158840,"shares_after":383607.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":11833.0,"price":200.1145,"value":2367955,"shares_after":371774.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13368.0,"price":200.7769,"value":2683986,"shares_after":358406.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":21447.0,"price":201.7507,"value":4326947,"shares_after":336959.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":18869.0,"price":203.0606,"value":3831550,"shares_after":318090.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":17949.0,"price":203.8726,"value":3659309,"shares_after":300141.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4995.0,"price":204.8427,"value":1023189,"shares_after":295146.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0001462808-26-000007","form":"4","filed":"2026-09-15","date":"2026-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3270.0,"price":205.8075,"value":672991,"shares_after":291876.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000146280826000007/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":9363.0,"price":33.62,"value":314784,"shares_after":59338.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":6019.0,"price":203.2844,"value":1223569,"shares_after":53319.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5530.0,"price":204.1357,"value":1128870,"shares_after":47789.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2420.0,"price":205.0513,"value":496224,"shares_after":45369.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1179.0,"price":206.0995,"value":242991,"shares_after":44190.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0002124509-26-000004","form":"4","filed":"2026-09-14","date":"2026-09-10","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":300.0,"price":207.1733,"value":62152,"shares_after":43890.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000212450926000004/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":706.0,"price":206.6049,"value":145863,"shares_after":16384.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":999.0,"price":207.3321,"value":207125,"shares_after":15385.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3587.0,"price":208.5534,"value":748081,"shares_after":11798.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2853.0,"price":209.56,"value":597875,"shares_after":8945.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4730.0,"price":210.5028,"value":995678,"shares_after":4215.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3844.0,"price":211.3588,"value":812463,"shares_after":371.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-388156","form":"4","filed":"2026-09-10","date":"2026-09-08","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":371.0,"price":212.2693,"value":78752,"shares_after":0.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526388156/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":300.0,"price":200.56,"value":60168,"shares_after":72790.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":6597.0,"price":201.4729,"value":1329117,"shares_after":66193.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":12919.0,"price":202.4819,"value":2615864,"shares_after":53274.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":26160.0,"price":203.5483,"value":5324824,"shares_after":27114.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":7271.0,"price":204.3501,"value":1485830,"shares_after":19843.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2128.0,"price":205.1879,"value":436640,"shares_after":17715.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001193125-26-380277","form":"4","filed":"2026-09-02","date":"2026-08-31","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":625.0,"price":206.154,"value":128846,"shares_after":17090.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000119312526380277/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":29680.0,"price":18.56,"value":550861,"shares_after":86201.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":26600.0,"price":21.61,"value":574826,"shares_after":112801.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3400.0,"price":207.2363,"value":704603,"shares_after":109401.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":17323.0,"price":208.3688,"value":3609573,"shares_after":92078.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":25817.0,"price":209.2497,"value":5402200,"shares_after":66261.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2540.0,"price":210.2647,"value":534072,"shares_after":63721.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4500.0,"price":211.3417,"value":951038,"shares_after":59221.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000388","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3314.0,"price":212.0583,"value":702761,"shares_after":55907.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000388/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":80000.0,"price":4.73,"value":378400,"shares_after":347330.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5128.0,"price":207.233,"value":1062691,"shares_after":342202.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":24917.0,"price":208.3697,"value":5191948,"shares_after":317285.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":35938.0,"price":209.2615,"value":7520440,"shares_after":281347.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3813.0,"price":210.2466,"value":801670,"shares_after":277534.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":6583.0,"price":211.3331,"value":1391206,"shares_after":270951.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3621.0,"price":212.0776,"value":767933,"shares_after":267330.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":190.0,"price":207.2454,"value":39377,"shares_after":64234.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":951.0,"price":208.3648,"value":198155,"shares_after":63283.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1351.0,"price":209.2812,"value":282739,"shares_after":61932.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":136.0,"price":210.4017,"value":28615,"shares_after":61796.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":245.0,"price":211.4651,"value":51809,"shares_after":61551.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":127.0,"price":212.0635,"value":26932,"shares_after":61424.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":177.0,"price":207.2515,"value":36684,"shares_after":64247.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":937.0,"price":208.3609,"value":195234,"shares_after":63310.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1405.0,"price":209.2664,"value":294019,"shares_after":61905.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":126.0,"price":210.403,"value":26511,"shares_after":61779.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":229.0,"price":211.4648,"value":48425,"shares_after":61550.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000387","form":"4","filed":"2026-08-25","date":"2026-08-21","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":126.0,"price":212.0641,"value":26720,"shares_after":61424.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000387/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":2955.0,"price":37.54,"value":110931,"shares_after":27236.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":300.0,"price":183.1733,"value":54952,"shares_after":26936.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":900.0,"price":184.5869,"value":166128,"shares_after":26036.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1100.0,"price":185.8991,"value":204489,"shares_after":24936.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":858.0,"price":186.9157,"value":160374,"shares_after":24078.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":300.0,"price":187.8267,"value":56348,"shares_after":23778.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":100.0,"price":188.57,"value":18857,"shares_after":23678.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":600.0,"price":190.545,"value":114327,"shares_after":23078.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":541.0,"price":191.8661,"value":103800,"shares_after":22537.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000311","form":"4","filed":"2026-07-01","date":"2026-06-29","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":881.0,"price":192.6139,"value":169693,"shares_after":21656.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000311/"},{"accession":"0001610717-26-000296","form":"4","filed":"2026-06-26","date":"2026-06-24","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":20000.0,"price":18.56,"value":371200,"shares_after":143269.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000296/"},{"accession":"0001610717-26-000296","form":"4","filed":"2026-06-26","date":"2026-06-24","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4553.0,"price":167.345,"value":761922,"shares_after":138716.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000296/"},{"accession":"0001610717-26-000296","form":"4","filed":"2026-06-26","date":"2026-06-24","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":9496.0,"price":168.1959,"value":1597188,"shares_after":129220.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000296/"},{"accession":"0001610717-26-000296","form":"4","filed":"2026-06-26","date":"2026-06-24","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5651.0,"price":169.2441,"value":956398,"shares_after":123569.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000296/"},{"accession":"0001610717-26-000296","form":"4","filed":"2026-06-26","date":"2026-06-24","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":300.0,"price":170.32,"value":51096,"shares_after":123269.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000296/"},{"accession":"0001610717-26-000290","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":74281.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000290/"},{"accession":"0001610717-26-000289","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Borisy Alexis","owner_cik":"0001319446","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":2340075.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000289/"},{"accession":"0001610717-26-000287","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":9406.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000287/"},{"accession":"0001610717-26-000286","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Horning Sandra","owner_cik":"0001638709","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":97765.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000286/"},{"accession":"0001610717-26-000285","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Clyburn Frank","owner_cik":"0001763963","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":10929.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000285/"},{"accession":"0001610717-26-000284","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":24281.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000284/"},{"accession":"0001610717-26-000281","form":"4","filed":"2026-06-23","date":"2026-06-18","owner":"Borellini Flavia","owner_cik":"0001867426","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":1191.0,"price":0.0,"value":null,"shares_after":26215.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000281/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":573.0,"price":40.74,"value":23344,"shares_after":155220.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3302.0,"price":29.8,"value":98400,"shares_after":158522.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":25725.0,"price":26.5,"value":681712,"shares_after":184247.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":29600.0,"price":160.1243,"value":4739679,"shares_after":154647.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000247","form":"4","filed":"2026-06-18","date":"2026-06-16","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4615.0,"price":156.1192,"value":720490,"shares_after":49975.0,"direct":true,"nature":null,"plan_10b5_1":false,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000247/"},{"accession":"0001610717-26-000246","form":"4","filed":"2026-06-18","date":"2026-06-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":10020.0,"price":156.1188,"value":1564310,"shares_after":267330.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000246/"},{"accession":"0001610717-26-000245","form":"4","filed":"2026-06-18","date":"2026-06-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2157.0,"price":156.1191,"value":336749,"shares_after":56521.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000245/"},{"accession":"0001610717-26-000244","form":"4","filed":"2026-06-18","date":"2026-06-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2722.0,"price":156.1192,"value":424956,"shares_after":123269.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000244/"},{"accession":"0001610717-26-000243","form":"4","filed":"2026-06-18","date":"2026-06-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4175.0,"price":156.1192,"value":651798,"shares_after":291876.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000243/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-15","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":15546.0,"price":40.74,"value":633344,"shares_after":173768.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-15","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":44854.0,"price":29.8,"value":1336649,"shares_after":218622.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2026-06-15","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":60400.0,"price":160.1706,"value":9674304,"shares_after":158222.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":1094.0,"price":42.45,"value":46440,"shares_after":159316.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":8906.0,"price":40.74,"value":362830,"shares_after":168222.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1315.0,"price":144.2793,"value":189727,"shares_after":166907.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":885.0,"price":145.1495,"value":128457,"shares_after":166022.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":700.0,"price":146.0371,"value":102226,"shares_after":165322.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":500.0,"price":147.272,"value":73636,"shares_after":164822.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1800.0,"price":148.7231,"value":267702,"shares_after":163022.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4600.0,"price":149.6429,"value":688357,"shares_after":158422.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000216","form":"4","filed":"2026-06-15","date":"2026-06-11","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":200.0,"price":150.17,"value":30034,"shares_after":158222.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000216/"},{"accession":"0001610717-26-000166","form":"4","filed":"2026-05-28","date":"2026-05-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3121.0,"price":33.62,"value":104928,"shares_after":57521.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000166/"},{"accession":"0001610717-26-000166","form":"4","filed":"2026-05-28","date":"2026-05-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":700.0,"price":153.3023,"value":107312,"shares_after":56821.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000166/"},{"accession":"0001610717-26-000166","form":"4","filed":"2026-05-28","date":"2026-05-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2000.0,"price":154.0609,"value":308122,"shares_after":54821.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000166/"},{"accession":"0001610717-26-000166","form":"4","filed":"2026-05-28","date":"2026-05-26","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":421.0,"price":154.8157,"value":65177,"shares_after":54400.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000166/"},{"accession":"0001610717-26-000158","form":"4","filed":"2026-04-29","date":"2026-04-27","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3120.0,"price":33.62,"value":104894,"shares_after":57520.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000158/"},{"accession":"0001610717-26-000158","form":"4","filed":"2026-04-29","date":"2026-04-27","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1671.0,"price":131.6619,"value":220007,"shares_after":55849.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000158/"},{"accession":"0001610717-26-000158","form":"4","filed":"2026-04-29","date":"2026-04-27","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1049.0,"price":132.8768,"value":139388,"shares_after":54800.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000158/"},{"accession":"0001610717-26-000158","form":"4","filed":"2026-04-29","date":"2026-04-27","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":400.0,"price":134.335,"value":53734,"shares_after":54400.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000158/"},{"accession":"0001610717-26-000146","form":"4","filed":"2026-04-17","date":"2026-04-15","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":23244.0,"price":4.09,"value":95068,"shares_after":299942.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000146/"},{"accession":"0001610717-26-000146","form":"4","filed":"2026-04-17","date":"2026-04-15","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":96756.0,"price":4.73,"value":457656,"shares_after":396698.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000146/"},{"accession":"0001610717-26-000146","form":"4","filed":"2026-04-17","date":"2026-04-15","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":120000.0,"price":150.0874,"value":18010488,"shares_after":276698.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000146/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":400.0,"price":97.21,"value":38884,"shares_after":54400.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":11036.0,"price":96.43,"value":1064201,"shares_after":54800.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":21086.0,"price":95.49,"value":2013502,"shares_after":65836.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3128.0,"price":94.16,"value":294532,"shares_after":86922.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1800.0,"price":93.22,"value":167796,"shares_after":90050.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000137","form":"4","filed":"2026-03-26","date":"2026-03-25","owner":"Mancini Anthony","owner_cik":"0002124509","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":37450.0,"price":33.62,"value":1259069,"shares_after":91850.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000137/"},{"accession":"0001610717-26-000127","form":"4","filed":"2026-03-19","date":"2026-03-19","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1163.0,"price":97.44,"value":113323,"shares_after":58518.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000127/"},{"accession":"0001610717-26-000132","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Wei Lin","owner_cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2073.0,"price":99.48,"value":206222,"shares_after":101366.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000132/"},{"accession":"0001610717-26-000131","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4302.0,"price":99.48,"value":427963,"shares_after":295398.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000131/"},{"accession":"0001610717-26-000130","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":12871.0,"price":99.48,"value":1280407,"shares_after":276698.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000130/"},{"accession":"0001610717-26-000129","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4583.0,"price":99.48,"value":455917,"shares_after":157570.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000129/"},{"accession":"0001610717-26-000128","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2753.0,"price":99.48,"value":273868,"shares_after":125512.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000128/"},{"accession":"0001610717-26-000127","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1795.0,"price":99.48,"value":178567,"shares_after":59681.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000127/"},{"accession":"0001610717-26-000126","form":"4","filed":"2026-03-19","date":"2026-03-17","owner":"Wang Xiaolin","owner_cik":"0001849181","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2010.0,"price":99.48,"value":199955,"shares_after":116063.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000126/"},{"accession":"0001610717-26-000087","form":"4","filed":"2026-03-06","date":"2026-03-04","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":true,"security":"Common Stock","shares":15000.0,"price":0.0,"value":null,"shares_after":15000.0,"direct":false,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000087/"},{"accession":"0001610717-26-000087","form":"4","filed":"2026-03-06","date":"2026-03-04","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":false,"security":"Common Stock","shares":15000.0,"price":0.0,"value":null,"shares_after":8215.0,"direct":true,"nature":"See footnote","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000087/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3620.0,"price":100.73,"value":364643,"shares_after":311749.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":21329.0,"price":101.6,"value":2167026,"shares_after":290420.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":100.0,"price":98.31,"value":9831,"shares_after":67324.0,"direct":false,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":400.0,"price":100.12,"value":40048,"shares_after":66924.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1700.0,"price":101.47,"value":172499,"shares_after":65224.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":800.0,"price":102.0,"value":81600,"shares_after":64424.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":100.0,"price":98.29,"value":9829,"shares_after":67324.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":600.0,"price":100.19,"value":60114,"shares_after":66724.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2100.0,"price":101.63,"value":213423,"shares_after":64624.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":200.0,"price":102.08,"value":20416,"shares_after":64424.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3500.0,"price":99.76,"value":349160,"shares_after":315369.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":700.0,"price":98.17,"value":68719,"shares_after":318869.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":30000.0,"price":4.09,"value":122700,"shares_after":319569.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-02","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":851.0,"price":102.2,"value":86972,"shares_after":289569.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000085","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Wang Xiaolin","owner_cik":"0001849181","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":15100.0,"price":0.0,"value":null,"shares_after":118073.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000085/"},{"accession":"0001610717-26-000084","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Wei Lin","owner_cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":15100.0,"price":0.0,"value":null,"shares_after":103439.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000084/"},{"accession":"0001610717-26-000083","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":21100.0,"price":0.0,"value":null,"shares_after":299700.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000083/"},{"accession":"0001610717-26-000082","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":57100.0,"price":0.0,"value":null,"shares_after":289569.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000082/"},{"accession":"0001610717-26-000081","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":21100.0,"price":0.0,"value":null,"shares_after":162153.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000081/"},{"accession":"0001610717-26-000080","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":14500.0,"price":0.0,"value":null,"shares_after":61476.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000080/"},{"accession":"0001610717-26-000079","form":"4","filed":"2026-03-03","date":"2026-03-01","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":20200.0,"price":0.0,"value":null,"shares_after":128265.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000079/"},{"accession":"0001610717-26-000048","form":"4","filed":"2026-02-10","date":"2026-02-06","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":24010.0,"price":0.54,"value":12965,"shares_after":256479.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000048/"},{"accession":"0001610717-26-000018","form":"4","filed":"2026-01-23","date":"2026-01-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":908.0,"price":115.6,"value":104965,"shares_after":46976.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000018/"},{"accession":"0001610717-26-000013","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":20204.0,"price":101.79,"value":2056565,"shares_after":142753.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000013/"},{"accession":"0001610717-26-000013","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":53096.0,"price":100.02,"value":5310662,"shares_after":162957.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000013/"},{"accession":"0001610717-26-000013","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":23594.0,"price":29.8,"value":703101,"shares_after":216053.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000013/"},{"accession":"0001610717-26-000013","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1700.0,"price":102.9,"value":174930,"shares_after":141053.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000013/"},{"accession":"0001610717-26-000013","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":51406.0,"price":42.45,"value":2182185,"shares_after":192459.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000013/"},{"accession":"0001610717-26-000012","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":10000.0,"price":98.0,"value":980000,"shares_after":108065.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000012/"},{"accession":"0001610717-26-000012","form":"4","filed":"2026-01-09","date":"2026-01-07","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":10000.0,"price":42.45,"value":424500,"shares_after":118065.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000012/"},{"accession":"0001610717-25-000424","form":"4","filed":"2025-12-18","date":"2025-12-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2688.0,"price":76.82,"value":206492,"shares_after":47884.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000424/"},{"accession":"0001610717-25-000423","form":"4","filed":"2025-12-18","date":"2025-12-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":15394.0,"price":76.82,"value":1182567,"shares_after":232469.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000423/"},{"accession":"0001610717-25-000422","form":"4","filed":"2025-12-18","date":"2025-12-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5447.0,"price":76.82,"value":418439,"shares_after":278600.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000422/"},{"accession":"0001610717-25-000421","form":"4","filed":"2025-12-18","date":"2025-12-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4847.0,"price":76.82,"value":372347,"shares_after":141053.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000421/"},{"accession":"0001610717-25-000420","form":"4","filed":"2025-12-18","date":"2025-12-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3104.0,"price":77.09,"value":239287,"shares_after":108065.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000420/"},{"accession":"0001610717-25-000404","form":"4","filed":"2025-11-26","date":"2025-11-25","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":5418.0,"price":17.0,"value":92106,"shares_after":116412.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000404/"},{"accession":"0001610717-25-000404","form":"4","filed":"2025-11-26","date":"2025-11-25","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5418.0,"price":74.0,"value":400932,"shares_after":110994.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000404/"},{"accession":"0001610717-25-000403","form":"4","filed":"2025-11-26","date":"2025-11-25","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":60000.0,"price":4.09,"value":245400,"shares_after":307863.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000403/"},{"accession":"0001610717-25-000403","form":"4","filed":"2025-11-26","date":"2025-11-25","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":60000.0,"price":75.08,"value":4504800,"shares_after":247863.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000403/"},{"accession":"0001610717-25-000403","form":"4","filed":"2025-11-26","date":"2025-11-25","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3000.0,"price":75.0,"value":225000,"shares_after":67424.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000403/"},{"accession":"0001610717-25-000384","form":"4","filed":"2025-11-20","date":"2025-11-18","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":20000.0,"price":70.38,"value":1407600,"shares_after":247863.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000384/"},{"accession":"0001610717-25-000384","form":"4","filed":"2025-11-20","date":"2025-11-18","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":20000.0,"price":4.09,"value":81800,"shares_after":267863.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000384/"},{"accession":"0001610717-25-000383","form":"4","filed":"2025-11-20","date":"2025-11-18","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":13388.0,"price":42.45,"value":568321,"shares_after":63813.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000383/"},{"accession":"0001610717-25-000383","form":"4","filed":"2025-11-20","date":"2025-11-18","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13388.0,"price":70.14,"value":939034,"shares_after":50425.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000383/"},{"accession":"0001610717-25-000380","form":"4","filed":"2025-11-14","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":20000.0,"price":65.07,"value":1301400,"shares_after":247863.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000380/"},{"accession":"0001610717-25-000380","form":"4","filed":"2025-11-14","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":20000.0,"price":4.09,"value":81800,"shares_after":267863.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000380/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":false,"security":"Common Stock","shares":50000.0,"price":0.0,"value":null,"shares_after":297863.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":false,"security":"Common Stock","shares":50000.0,"price":0.0,"value":null,"shares_after":247863.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":true,"security":"Common Stock","shares":50000.0,"price":0.0,"value":null,"shares_after":70424.0,"direct":false,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-12","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":true,"security":"Common Stock","shares":50000.0,"price":0.0,"value":null,"shares_after":54498.0,"direct":false,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000377","form":"4","filed":"2025-11-13","date":"2025-11-11","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":10000.0,"price":64.0,"value":640000,"shares_after":110994.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000377/"},{"accession":"0001610717-25-000377","form":"4","filed":"2025-11-13","date":"2025-11-11","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":10000.0,"price":17.0,"value":170000,"shares_after":120994.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000377/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-07","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":30000.0,"price":60.31,"value":1809300,"shares_after":347863.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-07","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":26479.0,"price":1.12,"value":29656,"shares_after":374342.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000375","form":"4","filed":"2025-11-12","date":"2025-11-07","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3521.0,"price":4.09,"value":14401,"shares_after":377863.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000375/"},{"accession":"0001610717-25-000368","form":"4","filed":"2025-10-20","date":"2025-10-17","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":12000.0,"price":36.57,"value":438840,"shares_after":62425.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000368/"},{"accession":"0001610717-25-000368","form":"4","filed":"2025-10-20","date":"2025-10-17","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":12000.0,"price":55.0,"value":660000,"shares_after":50425.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000368/"},{"accession":"0001610717-25-000367","form":"4","filed":"2025-10-20","date":"2025-10-17","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":10000.0,"price":1.12,"value":11200,"shares_after":462309.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000367/"},{"accession":"0001610717-25-000367","form":"4","filed":"2025-10-20","date":"2025-10-17","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":10000.0,"price":55.0,"value":550000,"shares_after":452309.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000367/"},{"accession":"0001610717-25-000367","form":"4","filed":"2025-10-20","date":"2025-10-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":10000.0,"price":1.12,"value":11200,"shares_after":462309.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000367/"},{"accession":"0001610717-25-000367","form":"4","filed":"2025-10-20","date":"2025-10-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":10000.0,"price":50.47,"value":504700,"shares_after":452309.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000367/"},{"accession":"0001610717-25-000361","form":"4","filed":"2025-10-15","date":"2025-10-13","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":25000.0,"price":48.54,"value":1213500,"shares_after":284047.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000361/"},{"accession":"0001610717-25-000361","form":"4","filed":"2025-10-15","date":"2025-10-13","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":25000.0,"price":4.73,"value":118250,"shares_after":309047.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000361/"},{"accession":"0001610717-25-000353","form":"4","filed":"2025-09-26","date":"2025-09-24","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1799.0,"price":44.26,"value":79624,"shares_after":50425.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000353/"},{"accession":"0001610717-25-000351","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Wei Lin","owner_cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2160.0,"price":45.82,"value":98971,"shares_after":88339.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000351/"},{"accession":"0001610717-25-000350","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5367.0,"price":45.82,"value":245916,"shares_after":284047.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000350/"},{"accession":"0001610717-25-000349","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13411.0,"price":45.82,"value":614492,"shares_after":452309.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000349/"},{"accession":"0001610717-25-000348","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4775.0,"price":45.82,"value":218790,"shares_after":145900.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000348/"},{"accession":"0001610717-25-000347","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1869.0,"price":45.82,"value":85638,"shares_after":52224.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000347/"},{"accession":"0001610717-25-000346","form":"4","filed":"2025-09-18","date":"2025-09-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2320.0,"price":45.82,"value":106302,"shares_after":110994.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000346/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-15","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1318.0,"price":46.93,"value":61854,"shares_after":289414.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-15","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":23682.0,"price":45.92,"value":1087477,"shares_after":290732.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-15","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":25000.0,"price":4.73,"value":118250,"shares_after":314414.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":55941.0,"price":44.48,"value":2488256,"shares_after":289414.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":44059.0,"price":43.58,"value":1920091,"shares_after":345355.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000339","form":"4","filed":"2025-09-15","date":"2025-09-11","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":100000.0,"price":4.73,"value":473000,"shares_after":389414.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000339/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-03","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5238.0,"price":40.17,"value":210410,"shares_after":113314.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-03","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":2049.0,"price":17.0,"value":34833,"shares_after":118552.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-03","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":3189.0,"price":4.73,"value":15084,"shares_after":116503.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-02","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4762.0,"price":40.02,"value":190575,"shares_after":113314.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-02","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":1948.0,"price":4.73,"value":9214,"shares_after":118076.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000326","form":"4","filed":"2025-09-04","date":"2025-09-02","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":2814.0,"price":2.68,"value":7542,"shares_after":116128.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000326/"},{"accession":"0001610717-25-000274","form":"4","filed":"2025-07-02","date":"2025-06-30","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":37000.0,"price":0.54,"value":19980,"shares_after":465720.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000274/"},{"accession":"0001610717-25-000273","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Horning Sandra","owner_cik":"0001638709","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":96574.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000273/"},{"accession":"0001610717-25-000272","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Patel Sushil","owner_cik":"0001860609","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":23090.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000272/"},{"accession":"0001610717-25-000271","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Kim Lorence H.","owner_cik":"0001643746","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":73090.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000271/"},{"accession":"0001610717-25-000270","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Borisy Alexis","owner_cik":"0001319446","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":2338884.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000270/"},{"accession":"0001610717-25-000269","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Borellini Flavia","owner_cik":"0001867426","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":25024.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000269/"},{"accession":"0001610717-25-000268","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Anderson Elizabeth M","owner_cik":"0001758247","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":3142.0,"price":0.0,"value":null,"shares_after":23215.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000268/"},{"accession":"0001610717-25-000267","form":"4","filed":"2025-06-30","date":"2025-06-26","owner":"Clyburn Frank","owner_cik":"0001763963","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":2806.0,"price":0.0,"value":null,"shares_after":9738.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000267/"},{"accession":"0001610717-25-000250","form":"4","filed":"2025-06-23","date":"2025-06-20","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1912.0,"price":39.61,"value":75734,"shares_after":54093.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000250/"},{"accession":"0001610717-26-000230","form":"4","filed":"2026-06-17","date":"2025-06-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3575.0,"price":156.1193,"value":558126,"shares_after":154647.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071726000230/"},{"accession":"0001610717-25-000242","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3510.0,"price":39.83,"value":139803,"shares_after":150675.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000242/"},{"accession":"0001610717-25-000241","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13496.0,"price":39.83,"value":537546,"shares_after":428720.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000241/"},{"accession":"0001610717-25-000240","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1878.0,"price":39.83,"value":74801,"shares_after":56005.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000240/"},{"accession":"0001610717-25-000239","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2170.0,"price":39.83,"value":86431,"shares_after":113314.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000239/"},{"accession":"0001610717-25-000238","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4289.0,"price":39.83,"value":170831,"shares_after":289414.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000238/"},{"accession":"0001610717-25-000237","form":"4","filed":"2025-06-18","date":"2025-06-16","owner":"Wei Lin","owner_cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2173.0,"price":39.83,"value":86551,"shares_after":90499.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000237/"},{"accession":"0001610717-25-000088","form":"4","filed":"2025-03-24","date":"2025-03-20","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2041.0,"price":38.71,"value":79007,"shares_after":57723.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000088/"},{"accession":"0001610717-25-000081","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1458.0,"price":39.04,"value":56920,"shares_after":59764.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000081/"},{"accession":"0001610717-25-000080","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":11738.0,"price":39.04,"value":458252,"shares_after":441564.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000080/"},{"accession":"0001610717-25-000079","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1864.0,"price":39.04,"value":72771,"shares_after":115006.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000079/"},{"accession":"0001610717-25-000078","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3058.0,"price":39.04,"value":119384,"shares_after":153533.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000078/"},{"accession":"0001610717-25-000077","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":3294.0,"price":39.04,"value":128598,"shares_after":293051.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000077/"},{"accession":"0001610717-25-000076","form":"4","filed":"2025-03-19","date":"2025-03-17","owner":"Wang Xiaolin","owner_cik":"0001849181","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"G","kind":"gift","acquired":false,"security":"Common Stock","shares":2718.0,"price":0.0,"value":null,"shares_after":102321.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000076/"},{"accession":"0001610717-25-000056","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":22000.0,"price":0.0,"value":null,"shares_after":61222.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000056/"},{"accession":"0001610717-25-000055","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":20400.0,"price":0.0,"value":null,"shares_after":116870.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000055/"},{"accession":"0001610717-25-000054","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":36600.0,"price":0.0,"value":null,"shares_after":296345.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000054/"},{"accession":"0001610717-25-000053","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":28600.0,"price":0.0,"value":null,"shares_after":156591.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000053/"},{"accession":"0001610717-25-000052","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Wei Lin","owner_cik":"0001872772","title":"Chief Medical Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":false,"security":"Common Stock","shares":20800.0,"price":0.0,"value":null,"shares_after":91651.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000052/"},{"accession":"0001610717-25-000051","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Wang Xiaolin","owner_cik":"0001849181","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":19000.0,"price":0.0,"value":null,"shares_after":105039.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000051/"},{"accession":"0001610717-25-000050","form":"4","filed":"2025-03-04","date":"2025-03-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"A","kind":"award","acquired":true,"security":"Common Stock","shares":97400.0,"price":0.0,"value":null,"shares_after":453302.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000050/"},{"accession":"0001610717-25-000012","form":"4","filed":"2025-01-22","date":"2025-01-21","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2406.0,"price":40.5,"value":97443,"shares_after":39222.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071725000012/"},{"accession":"0001610717-24-000548","form":"4","filed":"2024-12-20","date":"2024-12-18","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":30846.0,"price":0.49,"value":15115,"shares_after":355902.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000548/"},{"accession":"0001610717-24-000547","form":"4","filed":"2024-12-18","date":"2024-12-16","owner":"Horn Margaret A","owner_cik":"0001294192","title":"Chief Operating Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4329.0,"price":45.4,"value":196537,"shares_after":127991.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000547/"},{"accession":"0001610717-24-000546","form":"4","filed":"2024-12-18","date":"2024-12-16","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":11714.0,"price":45.4,"value":531816,"shares_after":325056.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000546/"},{"accession":"0001610717-24-000545","form":"4","filed":"2024-12-18","date":"2024-12-16","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":4663.0,"price":45.4,"value":211700,"shares_after":259745.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000545/"},{"accession":"0001610717-24-000544","form":"4","filed":"2024-12-18","date":"2024-12-16","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":1599.0,"price":45.4,"value":72595,"shares_after":41628.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000544/"},{"accession":"0001610717-24-000543","form":"4","filed":"2024-12-18","date":"2024-12-16","owner":"Anders Jack","owner_cik":"0001800668","title":"Chief Financial Officer","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2635.0,"price":45.4,"value":119629,"shares_after":96470.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000543/"},{"accession":"0001415889-24-028638","form":"4","filed":"2024-12-09","date":"2024-12-05","owner":"Schroeder Thilo","owner_cik":"0001776412","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"P","kind":"open-market buy","acquired":true,"security":"Common Stock","shares":543478.0,"price":46.0,"value":24999988,"shares_after":2096612.0,"direct":false,"nature":"By Nextech Crossover I SCSP","plan_10b5_1":false,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000141588924028638/"},{"accession":"0001415889-24-028638","form":"4","filed":"2024-12-09","date":"2024-12-05","owner":"Schroeder Thilo","owner_cik":"0001776412","title":null,"is_director":true,"is_officer":false,"is_ten_pct":false,"owners":null,"code":"P","kind":"open-market buy","acquired":true,"security":"Common Stock","shares":760869.0,"price":46.0,"value":34999974,"shares_after":760869.0,"direct":false,"nature":"By Nextech VIII SCSP","plan_10b5_1":false,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000141588924028638/"},{"accession":"0001610717-24-000525","form":"4","filed":"2024-11-19","date":"2024-11-15","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2554.0,"price":55.13,"value":140802,"shares_after":43080.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000525/"},{"accession":"0001610717-24-000522","form":"4","filed":"2024-11-15","date":"2024-11-13","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":16666.0,"price":4.09,"value":68164,"shares_after":281074.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000522/"},{"accession":"0001610717-24-000522","form":"4","filed":"2024-11-15","date":"2024-11-13","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":13778.0,"price":58.49,"value":805875,"shares_after":267296.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000522/"},{"accession":"0001610717-24-000522","form":"4","filed":"2024-11-15","date":"2024-11-13","owner":"Kelsey Stephen Michael","owner_cik":"0001462808","title":"See Remarks","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":2888.0,"price":59.45,"value":171692,"shares_after":264408.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000522/"},{"accession":"0001610717-24-000518","form":"4","filed":"2024-11-08","date":"2024-11-06","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":6000.0,"price":60.0,"value":360000,"shares_after":45634.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000518/"},{"accession":"0001610717-24-000518","form":"4","filed":"2024-11-08","date":"2024-11-06","owner":"Cislini Jeff","owner_cik":"0001969082","title":"General Counsel","is_director":false,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":6000.0,"price":36.57,"value":219420,"shares_after":51634.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000518/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-04","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":36600.0,"price":0.49,"value":17934,"shares_after":336770.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-04","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":50900.0,"price":55.56,"value":2828004,"shares_after":300170.0,"direct":true,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-04","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":50900.0,"price":4.09,"value":208181,"shares_after":351070.0,"direct":true,"nature":null,"plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5000.0,"price":55.02,"value":275100,"shares_after":20424.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":9100.0,"price":55.02,"value":500682,"shares_after":300170.0,"direct":true,"nature":"Trust","plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"M","kind":"option exercise","acquired":true,"security":"Common Stock","shares":9100.0,"price":4.09,"value":37219,"shares_after":309270.0,"direct":true,"nature":"Trust","plan_10b5_1":null,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"},{"accession":"0001610717-24-000517","form":"4","filed":"2024-11-05","date":"2024-11-01","owner":"Goldsmith Mark A","owner_cik":"0001246842","title":"See Remarks","is_director":true,"is_officer":true,"is_ten_pct":false,"owners":null,"code":"S","kind":"open-market sale","acquired":false,"security":"Common Stock","shares":5000.0,"price":55.03,"value":275150,"shares_after":20424.0,"direct":false,"nature":null,"plan_10b5_1":true,"url":"https://www.sec.gov/Archives/edgar/data/1628171/000161071724000517/"}]}